Meta-Analysisvery high evidence

Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials.

Lancet (London, England)·February 14, 2026·PMID 41655587

Why it matters

Statin product labels list many adverse effects based on lower-quality evidence, potentially deterring appropriate use. This large, rigorous analysis clarifies which effects are truly attributable to statins, enabling more accurate risk-benefit discussions and reducing unnecessary discontinuation.

Infographic summary of Assessment of adverse effects attributed to statin therapy in product labels: a meta-analysis of double-blind randomised controlled trials.
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