Cohort Studyhigh evidence
Risk of Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis After Initiation of Antiseizure Medication: A Danish Nationwide Cohort Study.
Neurology·August 11, 2026·PMID 42467870
Why it mattersSJS/TEN are life-threatening cutaneous adverse reactions, and antiseizure medications are a major cause. Updated absolute risk estimates across 25 agents, including newer ones, help neurologists counsel patients on rare but serious risks when initiating therapy.
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