Cohort Studyhigh evidence
Time-independent value of IV thrombolysis in stroke thrombectomy: Evidence from a multicenter cohort.
Clinical neurology and neurosurgery·November 1, 2026·PMID 42508138
Why it mattersThe role of IVT before EVT in late-presenting stroke patients is debated, and many systems bypass IVT when transfer times are long. These real-world data suggest IVT still offers functional benefit without safety penalty even beyond 4.5 hours, supporting its use in inter-hospital transfer protocols.
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