Systematic Reviewhigh evidence
Systematic Review of Pharmacologic Treatment for Migraine Prevention in Adults: Report of the AAN Guidelines Subcommittee and the American Headache Society.
Headache·August 31, 2026·PMID 42673583
Why it mattersMigraine prevention requires balancing efficacy, tolerability, and patient preference across episodic and chronic forms. This review consolidates high- and moderate-confidence evidence for both CGRP monoclonal antibodies and traditional oral preventives, offering clinicians a current, evidence-based reference for selecting therapy.
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