Randomized Trialhigh evidence
Brain Frailty Rather than Age Alone Mediates the Lack of Benefit for Endovascular Thrombectomy in the Elderly Population of the RESILIENT Trial.
Annals of neurology·May 10, 2026·PMID 42108689
Why it mattersFor neurologists and emergency physicians selecting stroke patients for thrombectomy, this study suggests that CT-based cSVD burden may be a more relevant predictor of treatment benefit than chronological age alone, potentially refining patient selection and avoiding futile interventions in those with high brain frailty.
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