Randomized Trialhigh evidence
Efficacy and safety of allogeneic mesenchymal precursor cells with and without hyaluronic acid for treatment of chronic low back pain: a prospective, randomized, double blind, concurrent-controlled 36-month study.
The spine journal : official journal of the North American Spine Society·September 1, 2025·PMID 40174800
Why it mattersThis study provides 36-month safety and efficacy data on a minimally invasive, nonopioid regenerative therapy for discogenic low back pain, highlighting a potential treatment option for patients with shorter chronic pain duration who have failed conservative care.

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