Randomized Trialhigh evidence
Electronic Nicotine-Delivery Systems for Smoking Cessation.
The New England journal of medicine·February 15, 2024·PMID 38354139
Why it mattersE-cigarettes are widely used for smoking cessation, but rigorous evidence on their efficacy and safety has been limited. This large trial provides high-quality data showing they can improve quit rates when added to counseling, though with a trade-off of prolonged nicotine dependence.

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