Randomized Trialhigh evidence
Long-Term Effects of a 5-Year Randomized Controlled Exercise Trial on Brain Volumes and Cognitive Function in Older Adults: A 4-Year Post-Intervention Follow-Up Study.
Sports medicine (Auckland, N.Z.)·April 18, 2026·PMID 41999477
Why it mattersIt challenges the assumption that higher exercise intensity always yields better brain outcomes in older adults, and highlights the importance of baseline fitness as a long-term predictor of brain health.
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