Cohort Studymoderate evidence
Dementia Risk in Patients with Comorbid Insomnia and Obstructive Sleep Apnea: A Propensity Score-Matched Cohort Study.
Sleep·August 25, 2026·PMID 42640940
Why it mattersPatients with comorbid insomnia and OSA represent a distinct, high-risk subgroup in sleep medicine. Recognizing COMISA may help clinicians identify individuals who warrant closer cognitive monitoring and earlier intervention, as insomnia appears to compound dementia risk beyond OSA alone.
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