Systematic Reviewhigh evidence
Lenacapavir as pre-exposure prophylaxis for HIV prevention.
The Cochrane database of systematic reviews·April 1, 2026·PMID 41919720
Why it mattersLenacapavir offers a twice-yearly injectable PrEP option that may overcome adherence barriers seen with daily oral PrEP, particularly in populations with high HIV incidence. Its substantial efficacy and favorable safety profile make it a promising addition to HIV prevention strategies.
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