Cohort Studyhigh evidence
Anticoagulant-Dependent Platelet Morphological Artefacts in Platelet-Rich Plasma Preparation: A Prospective Paired Study Comparing EDTA and Sodium Citrate with Implications for Orthobiologic Therapy.
Biomedicines·July 14, 2026·PMID 42512051
Why it mattersAnticoagulant choice directly distorts platelet morphological parameters used to assess PRP quality in orthobiologic therapy. Reliance on EDTA may falsely elevate metrics like MPV and large platelet ratio, leading clinicians to overestimate platelet activation and potentially compromise treatment decisions.
The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled