Randomized Trialhigh evidence

Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation.

American journal of respiratory and critical care medicine·September 1, 2025·PMID 40668865

Why it matters

It provides the first evidence that a simple biomarker-based classification can identify sepsis patients who may be harmed by liberal fluid resuscitation, offering a path toward precision fluid management in critical care.

Infographic summary of Molecular Phenotyping of Sepsis and Differential Response to Fluid Resuscitation.
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