Cohort Studyhigh evidence
Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort.
Intensive care medicine·September 9, 2026·PMID 42714473
Why it mattersWeaning failure carries a high mortality risk, and identifying distinct phenotypes may help clinicians recognize patients at risk for poor outcomes and guide discussions about goals of care and timing of life-sustaining therapy decisions.

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