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Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort.

Intensive care medicine·September 9, 2026·PMID 42714473

Why it matters

Weaning failure carries a high mortality risk, and identifying distinct phenotypes may help clinicians recognize patients at risk for poor outcomes and guide discussions about goals of care and timing of life-sustaining therapy decisions.

Infographic summary of Distinct weaning phenotypes in patients unsuccessful in weaning from invasive mechanical ventilation: a secondary analysis of the WEAN SAFE cohort.
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