Randomized Trialhigh evidence
HIgh versus STAndard blood Pressure target in hypertensive high-risk patients undergoing elective major abdominal surgery: the HISTAP multicenter randomized clinical trial.
Intensive care medicine·June 29, 2026·PMID 42370999
Why it mattersThis trial provides direct evidence that a higher intraoperative MAP target reduces organ dysfunction in a common high-risk surgical population, informing blood pressure management strategies in the operating room.
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