Randomized Trialhigh evidence
Lean Mass Gains, Cardiac Remodeling, and Muscle Oxidative Changes With High-Dose Salbutamol During Resistance Training: A Randomized Controlled Trial.
Scandinavian journal of medicine & science in sports·June 1, 2026·PMID 42274909
Why it mattersHigh-dose beta2-agonists are misused for leanness and performance, but this trial reveals trade-offs: augmented lean mass comes with impaired muscle oxidative capacity, blunted fitness gains, and possible adverse cardiac remodeling signals.
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