Randomized Trialhigh evidence

Liposuction versus conservative therapy for patients with lipoedema in Germany: a multicentre, randomised controlled clinical trial.

Lancet (London, England)·September 5, 2026·PMID 42692034

Why it matters

Lipoedema is a painful, chronic condition with limited effective treatments. This trial provides high-quality evidence that liposuction offers substantial pain relief and quality-of-life improvement compared with standard conservative therapy, informing treatment decisions for patients with moderate-to-severe leg pain.

Infographic summary of Liposuction versus conservative therapy for patients with lipoedema in Germany: a multicentre, randomised controlled clinical trial.
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