Randomized Trialhigh evidence
Economic Evaluation of Mindfulness-Oriented Recovery Enhancement for the Treatment of Opioid Misuse.
Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research·July 23, 2026·PMID 42492812
Why it mattersOpioid misuse in chronic pain patients drives morbidity and healthcare costs, yet scalable, evidence-based behavioral interventions with proven cost-effectiveness are scarce. MORE’s low cost per averted misuse case and favorable return on investment support its consideration for integration into pain and addiction treatment pathways.

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