Cohort Studyhigh evidence
Interplay of genetic predisposition, plasma metabolome and Mediterranean diet in dementia risk and cognitive function.
Nature medicine·November 1, 2025·PMID 40855194
Why it mattersIt provides evidence that metabolic pathways linked to dementia risk differ by genetic background, supporting the potential for genotype-guided dietary interventions. For specialists, this reinforces the value of personalized lifestyle counseling, especially in high-risk APOE4 carriers.

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