Randomized Trialhigh evidence
Multifocal Noninvasive Deep Brain Stimulation to Enhance Cognition in Mild Cognitive Impairment: A Crossover Trial.
JAMA network open·July 1, 2026·PMID 42406397
Why it mattersThis study provides early evidence that noninvasive dual-target neuromodulation can enhance working memory in MCI-LB, a population with early striatal degeneration and limited treatment options. It highlights a potential role for cerebellar stimulation in compensating for striatal dysfunction.
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