Randomized Trialhigh evidence
Significant Anxiolytic Effect and Enhanced Recovery Benefits of Perioperative Low-Dose Olanzapine in Patients with Anxiety Undergoing THA: A Randomized Controlled Trial.
The Journal of bone and joint surgery. American volume·April 10, 2026·PMID 41961954
Why it mattersAnxiety is common in THA patients and worsens pain and recovery. This study provides Level I evidence that a low-cost, generic medication can simultaneously address anxiety, pain, sleep, and nausea, potentially streamlining perioperative care.
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