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Neurological outcome of out-of-hospital cardiac arrest patients ventilated with continuous flow insufflation of oxygen: a multicenter observational study.

Resuscitation·August 1, 2026·PMID 42069041

Why it matters

CFIO devices were designed to reduce chest compression interruptions, but this large registry-based study raises concern that they may worsen neurological outcomes compared to standard BVM ventilation. Emergency physicians and EMS directors should reconsider routine CFIO use pending further evidence.

Infographic summary of Neurological outcome of out-of-hospital cardiac arrest patients ventilated with continuous flow insufflation of oxygen: a multicenter observational study.
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