Randomized Trialhigh evidence
Post-Prandial Glucose Levels Are Elevated by Metformin after High Intensity Exercise Training in Metabolic Syndrome.
Medicine and science in sports and exercise·July 21, 2026·PMID 42478174
Why it mattersClinicians managing metabolic syndrome often combine exercise and metformin, but this trial suggests metformin may counteract the glucose-lowering benefits of high-intensity exercise, potentially influencing prescription of exercise intensity in patients on metformin.
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