Randomized Trialhigh evidence
NSAID ingestion augments training-induced muscle hypertrophy and differentially affects muscle mRNA expression, but not strength gains, in trained men.
The Journal of physiology·October 26, 2025·PMID 41139248
Why it mattersNSAID use is common among athletes, yet its effects on training adaptations are unclear. This study suggests that while NSAIDs may augment muscle growth, they do not enhance strength, raising questions about their utility for performance.

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