Systematic Reviewhigh evidence
Leukocyte-rich versus leukocyte-poor platelet-rich plasma and hyaluronic acid for knee osteoarthritis: a systematic review and network meta-analysis.
Journal of orthopaedic surgery and research·February 2, 2026·PMID 41629990
Why it mattersFor clinicians offering injection therapy for knee OA, this analysis supports PRP over hyaluronic acid for symptom and functional benefit, while suggesting that leukocyte concentration does not clearly determine efficacy. That helps guide product selection and patient counseling.
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