Randomized Trialhigh evidence
Focused ultrasound to bilateral thalamic nuclei significantly improves human cognitive attention in a frequency- and intensity-dependent manner.
Brain stimulation·July 21, 2026·PMID 42480914
Why it mattersNon-invasive thalamic neuromodulation could offer a new tool for enhancing attention and alertness in clinical populations with arousal deficits or in performance optimization contexts, but parameter selection is critical given the bidirectional intensity effects observed.

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