Randomized Trialhigh evidence

Focused ultrasound to bilateral thalamic nuclei significantly improves human cognitive attention in a frequency- and intensity-dependent manner.

Brain stimulation·July 21, 2026·PMID 42480914

Why it matters

Non-invasive thalamic neuromodulation could offer a new tool for enhancing attention and alertness in clinical populations with arousal deficits or in performance optimization contexts, but parameter selection is critical given the bidirectional intensity effects observed.

Infographic summary of Focused ultrasound to bilateral thalamic nuclei significantly improves human cognitive attention in a frequency- and intensity-dependent manner.
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