Randomized Trialhigh evidence
Microbiota fasting-related changes ameliorate cognitive decline in obesity and boost ex vivo microglial function through the gut-brain axis.
Gut·October 8, 2025·PMID 40335161
Why it mattersObesity-related cognitive decline is a growing concern, and dietary strategies that target the gut-brain axis may offer a non-pharmacological intervention. This study provides mechanistic insight by showing that ADF-induced microbiota changes can enhance microglial function, a key process in neuroinflammation and cognition.
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