Meta-Analysishigh evidence
Comparison of Patellofemoral and Motion Outcomes Between Unrestricted Kinematic and Mechanical Alignment in Primary Total Knee Arthroplasty: A Systematic Review and Meta-Analysis.
The Journal of the American Academy of Orthopaedic Surgeons·August 17, 2026·PMID 42606828
Why it mattersPatellofemoral complications and stiffness remain concerns with kinematic alignment, but this analysis suggests unrestricted KA may improve motion and reduce soft-tissue releases without increasing early adverse events.

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