Basic Sciencelow evidence

A bio-adaptive physical hydrogel enables dynamic tissue engineering for tracheal reconstruction.

Nature communications·December 14, 2025·PMID 41392088

Why it matters

Long-segment tracheal defects lack effective clinical solutions. This bio-adaptive hydrogel strategy mimics developmental processes to regenerate complex tracheal tissues, potentially overcoming limitations of static scaffolds and offering a new avenue for functional organ reconstruction.

Infographic summary of A bio-adaptive physical hydrogel enables dynamic tissue engineering for tracheal reconstruction.
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