Randomized Trialhigh evidence

Efficacy and safety of tirofiban after successful endovascular reperfusion in acute ischaemic stroke (ATTRACTION) in China: a multicentre, double-blind, randomised controlled trial.

Lancet (London, England)·July 18, 2026·PMID 42341797

Why it matters

Despite successful thrombectomy, many patients do not achieve functional independence. This trial provides high-level evidence that adjunctive antiplatelet therapy with tirofiban may improve outcomes, but the numerical increase in intracranial hemorrhage warrants careful patient selection.

Infographic summary of Efficacy and safety of tirofiban after successful endovascular reperfusion in acute ischaemic stroke (ATTRACTION) in China: a multicentre, double-blind, randomised controlled trial.
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