Systematic Reviewhigh evidence
Effects of combined versus single supplementation of creatine and beta-alanine on aerobic and anerobic performance: a systematic review and network meta-analysis.
Journal of the International Society of Sports Nutrition·December 31, 2026·PMID 42384726
Why it mattersFor clinicians advising athletes on ergogenic supplements, this analysis clarifies that creatine monotherapy provides the most consistent performance benefits, while adding beta-alanine does not enhance outcomes. This helps streamline evidence-based supplement recommendations and avoid unnecessary polypharmacy.
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