Randomized Trialhigh evidence
Impact of introducing RTS,S/AS01E malaria vaccine on mortality in young children in Ghana, Kenya, and Malawi: an observational evaluation of a cluster-randomised implementation programme.
Lancet (London, England)·May 9, 2026·PMID 42107373
Why it mattersThis is the first large-scale evidence that routine malaria vaccination reduces all-cause child mortality in real-world settings, supporting accelerated deployment in high-burden African regions.
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