Case-Controlhigh evidence
Contemporary menopausal hormone therapy and thrombotic disease: nationwide nested case-control study.
BMJ (Clinical research ed.)·September 23, 2026·PMID 42778212
Why it mattersMenopausal hormone therapy prescribing requires balancing symptom relief against cardiovascular safety. This large, contemporary registry study provides updated absolute risk estimates and clarifies that transdermal formulations may offer a safer thrombotic profile than oral therapy, informing patient counseling and regimen selection.
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