Cohort Studymoderate evidence
Effects of inflammatory phenotypes in acute respiratory distress syndrome on mortality and partitioning of lung and chest wall mechanics in patients in the USA and Canada: a retrospective cohort study.
The Lancet. Respiratory medicine·July 1, 2026·PMID 42155495
Why it mattersARDS inflammatory phenotypes are known to predict outcomes and treatment response. This study clarifies that lung-protective ventilation targets may have differential prognostic importance by phenotype, which could guide risk stratification and future trial enrichment strategies.
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