Randomized Trialhigh evidence

Cytisinicline for 6 or 12 wk increased smoking cessation rates after treatment and up to 24 wk.

Annals of internal medicine·September 1, 2025·PMID 40889365

Why it matters

Cytisinicline offers a potential new pharmacotherapy option for smoking cessation, which is relevant for pain specialists managing patients where smoking worsens outcomes and complicates treatment.

Infographic summary of Cytisinicline for 6 or 12 wk increased smoking cessation rates after treatment and up to 24 wk.
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