Randomized Trialhigh evidence
Deferring Arterial Catheterization in Critically Ill Patients with Shock.
The New England journal of medicine·November 13, 2025·PMID 41159885
Why it mattersThis trial provides high-level evidence that a strategy of deferring routine early arterial catheterization in shock is noninferior to early invasive monitoring for 28-day mortality, potentially reducing procedural complications and resource use without compromising outcomes.

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