Cohort Studymoderate evidence
Estimating the daily milligrams of morphine equivalent of illicit fentanyl use in Los Angeles: Clinical and epidemiological implications.
Drug and alcohol dependence·August 1, 2026·PMID 42302710
Why it mattersClinicians in emergency and internal medicine frequently encounter patients using illicit fentanyl. Understanding the massive MME doses involved helps contextualize high overdose risk, extreme tolerance, and challenges during medication-assisted treatment induction.

The papers that matter, first.
MedLit ranks the medical literature into a specialty feed with concise summaries, evidence-aware triage, and visual takeaways.
§
MedLit · Evidence, Distilled