Randomized Trialhigh evidence
Testosterone Treatment in Prostate Cancer Survivors With Hypogonadism: A Randomized Clinical Trial.
JAMA internal medicine·July 1, 2026·PMID 42113507
Why it mattersMany guidelines still consider prostate cancer a contraindication to TRT due to lack of randomized evidence. This trial offers the first high-quality proof-of-concept that TRT can improve symptoms and quality of life without short-term biochemical recurrence in men with low-risk disease after definitive surgery.
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