Meta-Analysishigh evidence
IV Thrombolysis in the Extended Time Window for Acute Ischemic Stroke: An Updated Systematic Review and Meta-Analysis.
Neurology·August 11, 2026·PMID 42492020
Why it mattersMany stroke patients present outside the standard 4.5-hour window, and this analysis strengthens the evidence that IVT can still improve functional outcomes in selected patients identified by advanced imaging, without increasing mortality.

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