Meta-Analysishigh evidence

IV Thrombolysis in the Extended Time Window for Acute Ischemic Stroke: An Updated Systematic Review and Meta-Analysis.

Neurology·August 11, 2026·PMID 42492020

Why it matters

Many stroke patients present outside the standard 4.5-hour window, and this analysis strengthens the evidence that IVT can still improve functional outcomes in selected patients identified by advanced imaging, without increasing mortality.

Infographic summary of IV Thrombolysis in the Extended Time Window for Acute Ischemic Stroke: An Updated Systematic Review and Meta-Analysis.
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