Cohort Studyhigh evidence
Initial Treatment for Acute Low Back Pain and Risk of Opioid Use Disorder and Overdose.
JAMA network open·October 1, 2026·PMID 42895745
Why it mattersAcute low back pain is common, and initial treatment choices may influence long-term opioid-related harms. These findings quantify the risk associated with specific initial therapies and support nonpharmacologic approaches as first-line.
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