Randomized Trialmoderate evidence
Bicarbonate and Carbohydrate Co-Ingestion During Exercise in a Novel Gel Format Improves Time-Trial Performance After 3 h of Moderate-Intensity Exercise in Trained Cyclists.
Scandinavian journal of medicine & science in sports·October 1, 2026·PMID 42788859
Why it mattersProlonged exercise impairs high-intensity performance, and strategies to preserve durability are clinically relevant for athletes and active patients. This study shows that bicarbonate delivered in a gel during exercise can enhance subsequent time-trial performance without gastrointestinal distress, offering a practical alternative to pre-exercise loading protocols.

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