Cohort Studyhigh evidence

Non-invasive tests in metabolic dysfunction-associated steatotic liver disease: the LITMUS prospective multicentre diagnostic accuracy study.

Lancet (London, England)·October 31, 2026·PMID 42956772

Why it matters

With approved MASLD therapies emerging, reliable non-invasive tests are needed to identify patients with at-risk MASH and advanced fibrosis for treatment and trial enrollment. This study provides head-to-head performance data across many biomarkers, informing selection of testing strategies.

Infographic summary of Non-invasive tests in metabolic dysfunction-associated steatotic liver disease: the LITMUS prospective multicentre diagnostic accuracy study.
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