Systematic Reviewhigh evidence
Testosterone replacement in men with sexual dysfunction.
The Cochrane database of systematic reviews·January 15, 2024·PMID 38224135
Why it mattersTRT is widely promoted for sexual dysfunction even in men without clear testosterone deficiency. This high-quality synthesis provides moderate-certainty evidence that short-term TRT lacks clinically important benefits for erectile function or sexual quality of life in this population, informing more selective prescribing.
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