Meta-Analysishigh evidence
Effects of Collagen Supplements on Skin Aging: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
The American journal of medicine·September 1, 2025·PMID 40324552
Why it mattersCollagen supplements are widely marketed for skin aging, but this meta-analysis shows that apparent benefits are driven by industry-funded and lower-quality studies. For clinicians advising patients on anti-aging interventions, these findings highlight the importance of scrutinizing evidence quality and funding bias when evaluating nutraceuticals.
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