Meta-Analysisvery high evidence
Intensive vs Standard Blood Pressure Lowering in People With and Without Chronic Kidney Disease: A Systematic Review and Meta-Analysis.
JAMA cardiology·October 7, 2026·PMID 42842238
Why it mattersClinicians managing hypertension in patients with CKD often face uncertainty about the renal safety of intensive BP targets. This analysis clarifies that cardiovascular benefits are consistent across CKD and non-CKD populations, while the observed eGFR declines do not translate into higher kidney failure risk.
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