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Epithelial injury and inflammatory phenotypes for personalized ventilation in ARDS: Secondary analysis of the LIVE trial.

Chest·September 23, 2026·PMID 42777910

Why it matters

ARDS management currently avoids routine lung recruitment, but this study suggests that baseline epithelial injury, measured by sRAGE, may identify patients who could benefit from recruitment. This could enable personalized ventilation strategies in critical care, moving beyond one-size-fits-all approaches.

Infographic summary of Epithelial injury and inflammatory phenotypes for personalized ventilation in ARDS: Secondary analysis of the LIVE trial.
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