Cohort Studymoderate evidence
Psilocybin desynchronizes the human brain.
Nature·August 1, 2024·PMID 39020167
Why it mattersIt provides a mechanistic link between psilocybin-induced brain network desynchronization, subjective experience, and lasting neuroplastic changes, informing how psychedelics may treat conditions like depression or chronic pain by altering rigid brain patterns.

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