Cohort Studymoderate evidence
Timing of Coffee Intake Modifies Mortality Risk in Cardiovascular-Kidney-Metabolic Syndrome: A Cohort and Experimental Study.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology·June 15, 2026·PMID 42253139
Why it mattersFor clinicians managing CKM syndrome, this suggests that when patients drink coffee may be as important as how much they drink. Morning consumption could be a simple, modifiable behavior to discuss during lifestyle counseling.
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