Randomized Trialvery high evidence
Transcatheter Aortic-Valve Replacement for Asymptomatic Severe Aortic Stenosis.
The New England journal of medicine·January 16, 2025·PMID 39466903
Why it mattersCurrent guidelines recommend watchful waiting for asymptomatic severe aortic stenosis, but this trial provides high-quality evidence that early TAVR reduces major adverse events, primarily by preventing unplanned hospitalizations. It challenges the standard surveillance approach in low-risk patients.
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