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A corticospinal signature for interindividual pain sensitivity.

Nature communications·December 11, 2025·PMID 41381586

Why it matters

It provides the first validated corticospinal biomarker linking laboratory pain measures to clinical symptoms, offering a direct target for neuromodulation and a translational bridge from healthy to patient populations.

Infographic summary of A corticospinal signature for interindividual pain sensitivity.
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