Randomized Trialhigh evidence

The effect of intraoperative dexamethasone on glycaemic responses in people with diabetes mellitus: a preplanned analysis of the Perioperative ADministration of Dexamethasone and Infection trial.

British journal of anaesthesia·June 16, 2026·PMID 42303515

Why it matters

Anesthesiologists often avoid dexamethasone in diabetic patients due to hyperglycemia concerns, yet this analysis shows the glucose rise is modest and not linked to higher infection rates, supporting its use for PONV prophylaxis.

Infographic summary of The effect of intraoperative dexamethasone on glycaemic responses in people with diabetes mellitus: a preplanned analysis of the Perioperative ADministration of Dexamethasone and Infection trial.
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